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. 2013 Mar 27;14:112. doi: 10.1186/1471-2105-14-112

Table 6.

A comparison of MetaCyc (M) and KEGG (K) reaction attributes, for those attributes where one hundred or more objects have a value for that attribute

MetaCyc
 
KEGG
 
Attribute (M) Frequency (M) Attribute (K) Frequency (K)
Physiologically-Relevant?
10262
 
 
Creation-Date
10247
 
 
 
 
Rpair
8292
Creator
8090
 
 
EC-Number
7998
Enzyme
7632
Reaction-Direction
6660
 
 
Orphan?
5967
 
 
Credits
2779
 
 
Rxn-Locations
282
 
 
Spontaneous? 238    

Attributes are sorted based on the MetaCyc frequency column. Attribute Physiologically-Relevant? describes whether a reaction occurs in vivo. Reaction-Direction specifies the directionality of the reaction. Orphan? is true when no nucleotide or amino-acid sequence has been determined for any enzyme catalyzing this reaction [39,40]. Rxn-Locations specifies the cellular locations in which a reaction occurs (e.g., cytoplasm or mitochondrion). Spontaneous? specifies whether a reaction occurs spontaneously in living organisms and therefore requires no enzyme. KEGG reaction attribute data are derived from the KEGG REACTION dataset, and thus include glycan reactions.