Skip to main content
. Author manuscript; available in PMC: 2014 May 1.
Published in final edited form as: Cell Calcium. 2013 Mar 13;53(0):315–326. doi: 10.1016/j.ceca.2013.02.001

FIGURE 1.

FIGURE 1

A: TRPC1 expression in HuMCs and mouse BMMCs. Expression of TRPC1 in HuMC (left panel: Human ) and BMMCs (right panel: Mouse) was determined by RT-PCR. Human brain total RNA (predicted size 525 bp) and mouse brain total RNA (predicted size 525 bp), were used as positive controls. B: Anaphylactic responses in WT and Trpc1−/− mice. Mice were sensitized using 3 μg anti-DNP IgE mAb. After 24 h, mice received an injection of 200 μg DNP-HSA and the change in core body temperature was monitored for 2 h. Data are presented as the mean ± SEM. (*p<0.05, **p<0.01; two way ANOVA). N=10. C: Mice were injected with a bolus of histamine (5 μMoles) retro-orbitally and the change in body temperature was measured every 5 min for 2 h. N=3.