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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Gastroenterology. 2013 Feb 7;144(7):1466–1477.e9. doi: 10.1053/j.gastro.2013.01.057

Figure 5. Increased susceptibility to S. typhimurium in ZBP-89ΔInt mice.

Figure 5

(A) Mouse body weight at euthanization. Percent survival of WT, N = 20 (black) versus ZBP-89ΔInt N = 20 SL1344 infected mice (red) from 4 independent experiments. Log-rank test demonstrated a statistically significant difference between the 2 groups (P = 0.0165) (C) Colitis scores (D) H&E stains of colon from WT and ZBP-89ΔInt mice prior to infection; (E) Myeloperoxidase (MPO) activity; (F) Leukocyte cell count from colons of WT versus ZBP-89ΔInt mice before and after SL1344 infection for 6 days. *P < 0.05.