Table 1.

In Vivo ⁷Li T₂, Concentration, and Compartmentation Results for Rat Brain

Rat	Brain Total [Li] (mM)	T2i (ms)	T2e (ms)	T2mono (ms)	% Lii Biexponential Fit	% Lii Monoexponential Fit	% Variance Explained - Biexponential Fit	% Variance Explained - Monoexponential Fit	[Lii] (mM)	[Lie] (mM)
1	6.1	14.6	261	107	55.6	67.2	99.3	87.9	4.2	13.6
2	6.0	15.2	297	133	52.2	57.9	99.5	87.0	3.9	14.4
3	5.7	12.6	309	116	58.7	63.9	97.8	82.0	4.2	11.8
4	4.7	16.1	268	124	51.3	61.1	99.1	88.6	3.0	11.5
5	4.6	22.1	363	90	64.8	73.1	98.9	88.0	3.7	8.1
6	4.5	12.6	273	179	37.3	41.5	97.5	90.1	2.1	14.2
7	4.1	18.1	302	106	58.3	67.5	99.7	88.0	3.0	8.5
8a	3.8	13.4	241	109	53.6	66.4	98.7	88.0	2.6	8.8
9a	3.6	12.7	264	125	53.2	60.7	98.5	85.8	2.4	8.4
10b	3.5	17.3	450	104	63.0	68.2	97.8	80.6	2.8	6.5
11a	2.6	20.3	344	132	54.6	58.2	97.4	85.5	1.8	5.9
12c	2.5	5.2	235	149	54.2	52.2	96.7	80.8	1.7	5.7
13d,e	1.1	11.6	234	73	51.8	79.4	90.3	80.7	0.7	2.7
Mean ± std. dev.	4.06 ± 1.46	14.8 ± 4.3	295 ± 61	119 ± 27	54.5 ± 6.7	62.9 ± 9.5	97.8 ± 2.4	85.6 ± 3.4	2.8 ± 1.1	9.2 ± 3.6

^aDosed at 3.5 meq/kg. See Methods.

^bAnalysis based on 11 TE data points. TE 300 acquired but not used. See Methods.

^cAnalysis based on 10 TE data points. TE 80, 300 acquired but not used. See Methods.

^dAnalysis based on 8 TE data points. TE 125, 175, 225, 300 acquired but not used. See Methods.

^eDosed at 3.25 meq/kg. See Methods.