Figure 2. Blood bacteremia of S. suis highly virulent strain ST1 and epidemic strain ST7 is similar in C57BL/6 and TLR2−/− mice.
C57BL/6 mice (n = 13 mice per group) or TLR2−/− mice (n = 14 mice per group) were inoculated by intraperitoneal injection with 1×107 CFU of either S. suis strain P1/7 (ST1) or SC84 (ST7). At 6 h (panel A), day 1 (panel B), day 3 (panel C), and day 6 (panel D) post-infection, 5 μl of blood was harvested from the tail of infected mice and proper dilutions were plated on blood agar plate to assess blood bacteremia. Data of individuals are presented including geometric mean with 95% confidence interval. No significant differences (P>0.05) between infected TLR2−/− mice and their WT counterpart were observed as determined by ANOVA.