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. Author manuscript; available in PMC: 2014 Jun 1.
Published in final edited form as: Chem Biol Drug Des. 2013 Apr 11;81(6):695–706. doi: 10.1111/cbdd.12116

Table 1.

6-nitroquipazine (6-NQ) analogue affinities (Ki, nM) in SERT.

graphic file with name nihms444229u1.jpg
Compound n SERT
6-NQ 0 0.17 ± 0.03a
1 1 1300 ± 300
2 2 86.1 ± 8.5
3 3 495.7 ± 34.3
4 4 24.0 ± 2.6
5 5 80.5 ± 7.4
6 6 72.9 ± 8.1
7 7 54.1 ± 4.7
8 8 20.8 ± 3.8
9 9 1.8 ± 0.2
10 10 4.5 ± 0.7
11 11 12.6 ± 1.3
12 12 16.1 ± 1.2
a

From (6)