Table 2.

Effect of 8 (20 mg/kg), 10 (5 mg/kg) and 12 (10 mg/kg) on mice locomotor activity.

Treatment	Locomotor activity
	6 minutes	30 minutes
Vehicle	554 ± 46	1514 ± 173
8	453 ± 41	1409 ± 199
10	239 ± 41***	897 ± 120**
12	628 ± 55	1774 ± 187

Number of light beam crossings ± S.E.M. 8, 10 and 12 were injected ip 30 min before the test.

^***p<0.001,

^**p<0.01 vs. vehicle group, (n=10). 6 minutes: F(2,27)=18.47, P<0.001; 30 minutes: F(2,27)=6.505, P<0.01.