Table 2. Relative Abundance classes of urine protein biomarkers.

Class 1: 100 ng/ml–>10 ug/ml		Class 2: 10 ng/ml –100 ng/ml		Class 3: 1 ng/ml –10 ng/ml		Class 4: Non-standard units
Biomarker	Protein Family	Biomarker	Protein Family	Biomarker	Protein Family	Biomarker	Protein Family
THP	glycoprotein	IGFBP-7	growth modulator	Transthyretin	carrier protein	FSH	hormone
HSA	plasma Protein	HE4	glycoprotein	Kallikrein 10	serine protease	LH	hormone
SCC	glycoprotein	PSA	serine protease	Apolipoprotein AII	apolipoprotein	CA 15-3	cancer antigen
OPN	cytokine	EGF	growth factor	Apolipoprotein E	apolipoprotein	CA-125	cancer antigen
Calbindin	calcium binding	MPO	peroxidase	NSE	enolase	CA 19-9	cancer antigen
Clusterin	glycoprotein	Cystatin C	Protease Inhibitor	M-CSF	cytokine
Mammaglobin	glycoprotein	β2-Microglobulin	MHC-1 component	TIMP-2	MMP inhibitor
α1-Antitrypsin	protease Inhibitor	IGFBP-3	growth modulator	Fibronectin	extracellular matrix
		fPSA	protease	ANGPTL4	glycoprotein
		Thrombospondin	Anti-angiogenesis	GSTα	enzyme
		LOX-1	membrane receptor	sTNFRII	secreted receptor
		GST π	enzyme	MMP-8	MMP
		TFF-3	gut secretion	Complement C3	complement
		C-Peptide	peptide	CEA	glycoprotein
		Thrombomodulin	receptor	sICAM-1	adhesion molecule
		MDA-LDL	lipoprotein	Keratin-1,10,11	structural protein
		Adiponectin	hormone	Cortisol	hormone (steroid)
		Cathepsin D	protease	Angiogenin	ribonuclease
		Apolipoprotein A1	apolipoprotein	Complement H	complement
		α-2-Macroglobulin	plasma Protein	Involucrin	envelope protein
				Apolipoprotein B	apolipoprotein
				sgp130	cytokine
				MMP-7	MMP
				MMP-9	MMP
				H-FABP	growth inhibitor
				sVCAM-1	adhesion molecule
				PBEF	enzyme
				Complement C4	complement
				Keratin-6	structural protein
				sTNFRI	secreted receptor
				Cytokeratin 19	intermediate filament
				Endostatin	extracellular signalling
				OC	hormone
				NCAM	adhesion molecule

Biomarkers within each class listed in order of decreasing relative abundance; Biomarkers in bold indicate high molecular weight (>70 kDa).