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. 2013 May 28;8(5):e64158. doi: 10.1371/journal.pone.0064158

Table 2. Primary treatment and response in patients with extranodal natural killer (NK)/T-cell lymphoma.

Treatment Low-CRP group, n (%) High-CRP group, n (%) P
Patients treated 104 (94.5) 73 (97.3) 0.584
Treatment modalities 0.092
CT followed by RT 71 (64.5) 40 (53.3)
CT alone 24 (21.8) 30 (40.0)
RT alone 3 (2.7) 1 (1.3)
Surgery followed by CT 6 (5.5) 2 (2.7)
Best supportive care 6 (5.5) 2 (2.7)
Chemotherapy regimens 0.986
CHOP or CHOP-like 12 (11.9) 8 (11.1)
EPOCH 38 (37.6) 25 (34.7)
ATT 22 (21.8) 17 (23.6)
GEMOX+L-asp 27(26.7) 21 (29.2)
SMILE 2 (2.0) 1 (1.4)
Complete remission 86 (82.7) 39 (53.4) <0.001

Abbreviations: CRP: C-reactive protein; CT: chemotherapy; RT: radiotherapy; CHOP: cyclophosphamide+doxorubicin+vincristine+prednisone; EPOCH: etoposide+doxorubicin+vincristine+cyclophosphamide+prednisone; ATT: alternating triple therapy (CHOP-B, cyclophosphamide+doxorubicin+vincristine+bleomycin+prednisone; IMVP-16, ifosfamide+methotrexate+etoposide; DHAP, dexamethasone+cisplatin+cytarabine); GEMOX+L-asp: gemcitabine+oxaliplatin+L-asparaginase; SMILE: dexamethasone+methotrexate+ifosfamide+L-asparaginase+etoposide.