Table 1. Ko and contraction duration parameters at 37° and 24°C.
T (°C) | Peak Ko (mM) | t50 (seconds) | Burst duration (seconds) | Time between contractions (seconds) | |
37 | 18.8 ± 5.9 | 15.7 ± 2.8 | 22.2 ± 9.5 | 105 ± 94 | |
24 | 26.2 ± 9.9 | 29.8 ± 16.2 | 76.5 ± 23.5 | 436 ± 198 | |
0.0003 | 0.0001 | 0.0001 | 0.0001 | p1 |
For “Peak Ko“ and “t50”: At 37°C, n = 7, with 45 contractions analyzed. At 24°C, n = 6, with 38 contractions analyzed. Data were measured under no flow conditions. For “Burst duration” and “Time between contractions”, data were obtained under flow conditions on the same tissue at both temperatures, first at 24° then at 37°C. n = 3, with 5 contractions analyzed for each experiment at both 24°C and 37°C.
1. For peak “Ko“ and “t50” data were unpaired and p values were obtained using the 2-tailed t-test. For “Burst duration” and “Time between contractions”, p values were obtained using the paired t-test.