Table 1. Differential gene expression in wildtype and PAI-1 knockout hearts.

Gene Symbol	Gene Name Upregulated (A)	p value
Ankrd1	Ankyrin repeat domain1	0.04
Dbp	D site albumin binding protein	0.03
Fxyd6	FXYD domain containing ion transport regulator 6	0.003
Fbln2	Fibulin 2	0.03
Pi16	Protease inhibitor 16	0.02
Phlda 1	Pleckstrin homology-like domain family Amember 1	0.002
Gene Symbol	Gene Name Downregulated (B)	p value
Taf6	Transcription initiation factor TFIID subunit 6	0.00002
H2-Ab1	Histocompatibility 2, class II antigen A, beta 1	0.03
Zfp68	Zinc finger protein 68	0.0000001
Acot 1	Acyl-CoA thioesterase 1	0.02
Spon2	Spondin 2	0.001
Ces1d	Carboxylesterase 1D	0.04

Genes upregulated (>1.5 fold) in knockout hearts compared to wildtype hearts (A). Genes downregulated (<1.5 fold) in knockout hearts compared to wildtype hearts (B).