Table 4. Differential gene expression in wildtype hearts and kidneys (Unique).
GeneSymbol | Gene Name Upregulated (A) | p-value |
Agtr1a | angiotensin II receptor, type 1a | 0.000002 |
Vegfc | vascular endothelial growth factor C | 0.0000008 |
Hbb-b1 | hemoglobin, beta adult major chain | 0.001 |
Taf9 | TAF9 RNA polymerase II, TBP associated factor 9 | 0.000002 |
Fgf1 | fibroblast growth factor 1 | 0.0004 |
Foxn3 | forkhead box n3 | 0.000001 |
Rb1 | retinoblastoma 1 | 0.00001 |
Tbrg1 | transforming growth factor beta regulated gene 1 | 0.00002 |
Sirt2 | sirtuin 2 | 0.00002 |
Apoe | apolipoprotein E | 0.03 |
Mdm2 | transformed mouse 3T3 cell double minute | 0.0000002 |
nfkb1 | nuclear factor of kappa light polypeptide | 0.0000001 |
Ier3ip1 | immediate early response 3 interacting protein1 | 0.0000005 |
Prlr | prolactin receptor | 0.000002 |
Nfatc1 | nuclear factor of activated T-cells | 0.00003 |
Gene Symbol | Gene Name Downregulated (B) | p-value |
Zfp36 | zinc finger protein 36 | 0.0004 |
Ctgf | connective tissue growth factor | 0.0006 |
Dusp6 | dual specificity phosphatase 6 | 0.0001 |
Ubtf | upstream binding transcription factor | 0.00002 |
Ier3 | immediate early response 3 | 0.00001 |
Dapk2 | death-associated protein kinase 2 | 0.000003 |
Sdc2 | syndecan 2 | 0.000005 |
Mapk13 | mitogen-activated protein kinase 13 | 0.0000004 |
Junb | Jun-B oncogene | 0.03 |
Genes upregulated (>1.5 fold) in wildtype hearts compared to wildtype kidneys (A). Genes downregulated (<1.5 fold) in wildtype hearts compared to wildtype kidneys (B).