Table II.
Physicochemical Properties of the Prepared Etodolac Lipid Matrix Tablets (mean ± S.D.)
Form. code | Tablet thickness (mm) | Tablet weight (mg) | Drug content (%) | Tablet friability (%) |
---|---|---|---|---|
L1 | 2.02 ± 0.04 | 402.14 ± 1.63 | 97.36 ± 0.33 | 0.36 ± 0.12 |
L2 | 2.01 ± 0.02 | 396.39 ± 1.34 | 99.67 ± 1.29 | 0.25 ± 0.15 |
L3 | 1.98 ± 0.1 | 397.98 ± 2.05 | 101.45 ± 1.23 | 0.34 ± 0.18 |
L4 | 1.92 ± 0.03 | 405.87 ± 2.12 | 103.12 ± 0.96 | 0.21 ± 0.19 |
L5 | 2.06 ± 0.04 | 404.23 ± 1.87 | 98.54 ± 1.11 | 0.29 ± 0.11 |
L6 | 2.04 ± 0.05 | 393.81 ± 2.18 | 102.34 ± 1.24 | 0.32 ± 0.14 |
L7 | 2.02 ± 0.06 | 395.14 ± 2.23 | 99.32 ± 1.35 | 0.37 ± 0.18 |
L8 | 2.09 ± 0.07 | 397.66 ± 3.11 | 97.66 ± 1.98 | 0.34 ± 0.12 |
L9 | 1.91 ± 0.04 | 405.11 ± 1.15 | 102.92 ± 1.16 | 0.49 ± 0.15 |
L10 | 2.05 ± 0.09 | 407.87 ± 1.26 | 101.88 ± 1.17 | 0.27 ± 0.17 |
L11 | 1.93 ± 0.10 | 408.10 ± 1.89 | 100.85 ± 1.34 | 0.29 ± 0.19 |
L12 | 2.04 ± 0.04 | 404.56 ± 1.11 | 99.23 ± 0.31 | 0.31 ± 0.17 |
L13 | 1.96 ± 0.08 | 402.17 ± 1.17 | 98.33 ± 1.95 | 0.40 ± 0.14 |
L14 | 1.94 ± 0.05 | 395.88 ± 2.76 | 99.42 ± 1.34 | 0.27 ± 0.11 |
L15 | 2.01 ± 0.07 | 396.23 ± 2.32 | 102.34 ± 1.78 | 0.36 ± 0.10 |
L16 | 2.02 ± 0.10 | 399.53 ± 2.98 | 103.30 ± 1.11 | 0.35 ± 0.15 |
L17 | 1.99 ± 0.03 | 400.45 ± 1.24 | 100.94 ± 0.93 | 0.39 ± 0.13 |
L18 | 2.03 ± 0.08 | 396.67 ± 2.70 | 100.60 ± 1.18 | 0.41 ± 0.19 |
L19 | 1.92 ± 0.07 | 403.24 ± 1.21 | 98.78 ± 0.32 | 0.47 ± 0.18 |
L20 | 1.94 ± 0.02 | 395.88 ± 2.95 | 99.45 ± 0.84 | 0.34 ± 0.16 |
L21 | 1.99 ± 0.06 | 397.17 ± 2.65 | 102.23 ± 1.72 | 0.38 ± 0.17 |
L22 | 2.02 ± 0.09 | 400.45 ± 1.98 | 103.78 ± 0.37 | 0.41 ± 0.18 |
L23 | 1.97 ± 0.08 | 395.67 ± 3.00 | 99.75 ± 1.93 | 0.36 ± 0.14 |
L24 | 1.93 ± 0.06 | 396.45 ± 3.08 | 101.14 ± 1.28 | 0.49 ± 0.19 |
L25 | 1.99 ± 0.08 | 397.78 ± 3.11 | 102.44 ± 1.27 | 0.36 ± 0.16 |
L26 | 2.08 ± 0.03 | 404.13 ± 1.10 | 100.82 ± 0.47 | 0.28 ± 0.14 |
L27 | 1.97 ± 0.04 | 401.30 ± 1.21 | 102.45 ± 0.48 | 0.50 ± 0.17 |
L28 | 2.05 ± 0.05 | 404.46 ± 1.01 | 99.45 ± 0.87 | 0.47 ± 0.11 |