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Solubility of TEL in SDs Prepared by Different Excipients
| Excipients | Solubility (μg/mL) |
|---|---|
| PEG 6000 | 0.31 ± 0.04 |
| PVP k30 | 0.25 ± 0.02 |
| Poloxamer 188 | 0.22 ± 0.02 |
| HP-β-CD | 0.25 ± 0.05 |
| CS | 3.48 ± 0.13 |
| MCC | 0.22 ± 0.03 |
TEL telmisartan, SD solid dispersion, PEG 6000 polyethylene glycol, PVP k30 polyvinylpyrrolidone, HP-β-CD hydroxypropyl-β-cyclodextrin, CS chitosan, MCC microcrystalline cellulose
