Dissolution profiles of different suspension amounts (φ) when the dissolution medium and agitation speed were fixed at pH 1.2 and 120 rpm at 37°C. a
φ = 1/4, b
φ = 1, c
φ = 3. Square, round, and triangle symbols stand for the suspensions with particle size 340, 560, and 1,300 nm, respectively (n = 3–6)