Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Model of the change in population of inter-domain orientations of Ub in the E3/E2~Ub complex. Our data is consistent with a model of Ub flexibility allowing a large range of relative orientations in E2~Ub (left). Upon binding to a RING/U-box domain Ub is restricted somewhat such that it is not rigid but distribution of conformations is more populated in the ‘closed’ state (right).
