Table 2.
Characteristics of obese and nonobese men with mild-to-moderate and severe obstructive sleep apnea.
| Variable | Nonobese mild-to-moderate OSA (n = 14) |
Obese mild-to-moderate OSA (n = 8) |
Nonobese severe OSA (n = 9) |
Obese severe OSA (n = 15) |
|---|---|---|---|---|
| Age (yearns) | 45.5 (41–48) | 43.0 (39–46) | 48.0 (32–54) | 37.0 (34–48) |
| Epworth Sleepiness Scale | 10.5 (4.0–12.0) | 10.0 (5.5–12.5) | 10.0 (4.0–15.0) | 11.0 (10.0–17.0) |
| BMI (kg/m2) | 28.2 (28.1–28.7)†# | 34.1 (31.3–38.4)∗¥ | 28.4 (27.5–29.8)†# | 37.4 (33.8–38.7)∗¥ |
| Waist (cm) | 100 (95–102)†# | 115 (110–118)∗¥ | 97 (96–101)†# | 118 (112–126)∗¥ |
| Polysomnographic parameters: | ||||
| AHI (events/h) | 12.7 (8.5–19.9)¥# | 16.2 (9.1–19.4)¥# | 53.5 (35.5–59.4)∗†# | 65.3 (74.2–91.4)∗†¥ |
| Arousal index (events/h) | 21.7 (18.9–27.5)¥# | 19.9 (14.5–24.3)¥# | 38.2 (33.4–59.4)∗†# | 59.1 (48.5–79.9)∗†¥ |
| Oxygen desaturation index (events/h) | 11.5 (7.1–13.7)¥# | 15.6 (9.9–18.9)¥# | 48.8 (27.1–56.3)∗†# | 76.1 (72.2–78.9)∗†¥ |
| Average SpO2 (%) | 96.0 (94.0–96.0)# | 94.5 (94.0–95.5)# | 95.0 (93.0–95.0)# | 91.0 (87.5–92.0)∗†¥ |
| Total sleep time SpO2 < 90% (%) | 0.1 (0–1.4)# | 0.8 (0.3–2.0)# | 5.3 (2.5–7.2)# | 34.5 (23.2–53.2)∗†¥ |
| Lipid profile: | ||||
| Total cholesterol (mmol/L) | 5.90 (4.92–6.64) | 5.64 (5.29–6.69) | 5.46 (4.91–6.07) | 5.15 (4.93–6.24) |
| High-density lipids (mmol/L) | 1.01 (0.96–1.05) | 0.76 (0.70–0.86) | 0.95 (0.81–1.20) | 0.91 (0.80–1.02) |
| Low-density lipids (mmol/L) | 3.84 (3.37–4.86) | 3.74 (3.61–4.51) | 3.22 (3.05–3.71) | 3.75 (3.32–3.94) |
| Triglycerides (mmol/L) | 1.14 (0.86–2.41) | 2.06 (1.84–2.67) | 1.22 (0.85–2.56) | 1.70 (1.19–2.92) |
Data is presented as median (25th and 75th percentiles). Comparisons of variables among four groups were made with Kruskal-Wallis test, followed by Bonferroni test. OSA: obstructive sleep apnea. *P < 0.05 versus nonobese mild-to-moderate OSA, † P < 0.05 versus obese mild-to-moderate OSA, ¥ P < 0.05 versus nonobese severe OSA, # P < 0.05 versus obese severe OSA.