Table 1.
Demographic and clinical data of study participants.
| Parameter | Baseline | 8 weeks (LOCF) | Reduction from baseline (%) | Statistics |
|---|---|---|---|---|
| Gender | ||||
| Male, n (%) | 11 (43.2%) | — | — | — |
| Female, n (%) | 14 (56.8%) | — | — | — |
| Age, years: mean (SD) | 32.0 (5.1) | — | — | — |
| Age at onset, years: mean (SD) | 25.0 (5.1) | — | — | — |
| Duration of illness, years: mean (SD) | 8.0 (2.8) | — | — | — |
| Experience of hospitalizations: yes, n (%) | 9 (36%) | — | — | — |
| History of suicidal attempt: yes, n (%) | 6 (24%) | — | — | — |
| HAM-D total score: mean (SD) | 28.0 (2.9) | 10.9 (5.5) | 61.1 | F = 131.3, df = 8, P < 0.001 |
| SHAPS total score: mean (SD) | 6.9 (2.2) | 3.6 (2.5) | 52 | t = 5.0, df = 48, P < 0.001 |
| SDS total score: mean (SD) | 16.6 (3.2) | 6.7 (5.2) | 61.6 | t = 8.2, df = 48, P < 0.001 |
HAM-D: Hamilton Rating Scale for Depression; SHAPS: Snaith-Hamilton Pleasure Scale; SDS: Sheehan Disability Scale (SDS).