Table 2.
Gravimetric analysis of mice after 1 and 4 weeks sham/TAC
| Sham | 1-week TAC | 4-weeks TAC | |
|---|---|---|---|
| Final − initial body weight (g) | 0.85 (0.47) | 0.19 (1.17) | −0.73 (0.51)* |
| Tibia length (mm) | 17.0 (0.45) | 16.9 (0.4) | 17.2 (0.6) |
| Wet HW (mg) | 108.2 (19.3) | 241.3 (20.8)* | 300.6 (35.8)*§ |
| HW/BW (mg g−1) | 5.17 (0.80) | 11.56 (1.63)* | 13.32 (1.89)* |
| HW/TL (mg mm−1) | 6.35 (1.11) | 14.28 (1.40)* | 17.50 (2.23)*§ |
| Dry LW (mg) | 51.8 (4.9) | 50.8 (5.0) | 94.9 (35.7)*§ |
| LW/BW (mg g−1) | 2.49 (0.29) | 2.42 (0.19) | 4.29 (1.50)*§ |
| LW/TL (mg mm−1) | 3.05 (0.30) | 3.01 (0.31) | 5.48 (1.96)*§ |
HW, heart weight; HW/BW, heart weight-to-body weight ratio; HW/TL, heart weight-to-tibia length ratio; LW, lung weight; LW/BW, lung weight-to-body weight ratio; LW/TL, lung weight-to-tibia length ratio; TAC, transverse aortic constriction.
Data are presented as mean (SD).
*
P < 0.05 vs. sham.
§
P < 0.05 vs. 1-week TAC.