Table 2.
3H-R-BrP clearance (K f*) and 14C-P clearance into storage products (K fs) in individual tissues of lean and obese Zucker rats in vivo.
| K f* (mL 100 g−1 min−1) | K fs (mL 100 g−1 min−1) | |||
|---|---|---|---|---|
| Lean | Obese | Lean | Obese | |
| Cerebellum | 0.46 ± 0.05 | 0.48 ± 0.04 | 0.87 ± 0.07 | 0.79 ± 0.05 |
| Liver | 37.5 ± 2.8 | 32.3 ± 2.3 | 45.9 ± 4.4 | 38.9 ± 2.8 |
| WAT | 0.69 ± 0.05 | 0.70 ± 0.06 | 1.6 ± 0.1 | 1.4 ± 0.2 |
| BAT | 7.2 ± 0.6 | 3.6 ± 0.5*** | 9.4 ± 1.0 | 7.8 ± 1.4 |
| Heart | 29.3 ± 2.8 | 16.5 ± 1.4** | 15.5 ± 1.2 | 17.0 ± 3.3 |
K f* indexes the ability of the tissue to take up and utilize FA (for both oxidation and storage); K fs indexes the ability to store FA. Data are mean ± SE (n = 6 per group).
*P < 0.05, **P < 0.01, ***P < 0.001 versus Lean.