Table 2.
Baseline laboratory values.
| Variable | All (N = 91) | Bendamustine monotherapy (n = 10) | Bendamustine + rituximab combination therapy (n = 6) | Bendamustine monotherapy (n = 20) | Bendamustine + rituximab combination therapy (n = 55) |
|---|---|---|---|---|---|
| Hemoglobin (mg/dl) | |||||
| Mean (SD) | 11.5 (1.7) | 12.3 (2.2) | 11.7 (1.4) | 11.1 (1.5) | 11.5 (1.6) |
| Median (range) | 11.4 (7.5–16.3) | 11.8 (9.8–16.3) | 12.5 (9.2–13.0) | 11.1 (8.3–15.2) | 11.7 (7.5–14.2) |
| Hematocrit (%) | |||||
| Mean (SD) | 34.5 (4.9) | 37.3 (7.1) | 34.6 (4.3) | 33.3 (4.4) | 34.5 (4.7) |
| Median (range) | 34.5 (22.9–48.8) | 36.4 (28.3–48.8) | 35.9 (27.7–38.4) | 33.2 (24.9–46.4) | 35.1 (22.9–42.4) |
| Missing | 1 | 0 | 0 | 0 | 1 |
| Creatinine (mg/dl) | |||||
| Mean (SD) | 1.2 (0.4) | 1.2 (0.3) | 1.2 (0.28) | 1.1 (0.3) | 1.2 (0.4) |
| Median (range) | 1.1 (0.5–2.7) | 1.08 (0.87–1.8) | 1.1 (0.87–1.6) | 1.04 (0.58–2.0) | 1.1 (0.67–2.7) |
| Missing | 1 | 0 | 1 | 0 | 0 |
| Lactate dehydrogenase (U/liter) | |||||
| Mean (SD) | 247.6 (108.9) | 301.3 (146.3) | 299 (126.8) | 199.1 (78.9) | 254.8 (107) |
| Median (range) | 232.5 (95–636) | 295 (109–577) | 286 (189–435) | 184 (95–354) | 242.5 (110–636) |
| Missing | 13 | 2 | 2 | 0 | 9 |
| White blood cell count (× 103/µl) | |||||
| Mean (SD) | 61.8 (74.4) | 144.2 (121.4) | 40.2 (37.0) | 63.6 (58.9) | 49.3 (63.1) |
| Median (range) | 39 (2.5–395) | 98.5 (37.8–395) | 26.1 (8.0–90.5) | 40.6 (5.0–191) | 20 (2.5–266.5) |
| Missing | 9 | 1 | 0 | 4 | 4 |
| Neutrophils (× 103/µl) | |||||
| Mean (SD) | 6.4 (10.2) | 13.1 (19.8) | 5.9 (3.7) | 6.4 (10.7) | 5.4 (7.9) |
| Median (range) | 3.5 (0.5–62.0) | 6.3 (3.8–62.0) | 4.8 (3.0–13.1) | 3.3 (0.9–44.1) | 3.0 (0.5–44.5) |
| Missing | 16 | 2 | 0 | 5 | 9 |
| Lymphocytes (× 103/µl) | |||||
| Mean (SD) | 49.2 (59.8) | 97.0 (82.2) | 33.9 (30.0) | 55.2 (52.4) | 40.6 (57.4) |
| Median (range) | 32.3 (0.7–276.4) | 56.9 (29.3–276.5) | 34.2 (3.8–66.9) | 36.0 (2.8–163.4) | 13.9 (0.7–206.4) |
| Missing | 17 | 2 | 1 | 5 | 9 |
| Platelets (× 103/µl) | |||||
| Mean (SD) | 139.8 (66.7) | 127.3 (43.2) | 163.6 (71.9) | 118.3 (67.1) | 146.5 (67.9) |
| Median (range) | 126.5 (16.0–351) | 134 (70.0–179.0) | 143.5 (74.0–262.0) | 106 (16.0–281.0) | 132.5 (47.0–351.0) |
| Missing | 7 | 3 | 0 | 1 | 3 |
SD, standard deviation.