Table 5.
Variable, n (%) | All (N = 91) | Treatment naïve |
Relapsed or ≥second line |
||
---|---|---|---|---|---|
Bendamustine monotherapy (n = 10) | Bendamustine + rituximab combination therapy (n = 6) | Bendamustine monotherapy (n = 20) | Bendamustine + rituximab combination therapy (n = 55) | ||
Overall response rate* [95% CI] | 53 (58.2) [47.4–68.5] | 5 (50.0) [18.7–81.3] | 4 (66.7) [22.3–95.6] | 9 (45.0) [23.0–68.4] | 35 (63.6) [49.5–76.2] |
Complete response [95% CI] | 13 (14.3) [7.8–23.2] | 1 (10.0) [0.25–44.5] | 2 (33.3) [4.3–77.7] | 4 (20.0) [5.7–43.6] | 6 (10.9) [4.1–22.2] |
Partial response [95% CI] | 39 (42.9) [32.5–53.6] | 4 (40.0) [12.1–73.7] | 2 (33.3) [4.3–77.7] | 5 (25.0) [8.6–49.1] | 28 (50.9) [37.0–64.6] |
Nodular partial response | 1 (1.1) | 0 | 0 | 0 | 1 (1.8) |
Stable disease | 14 (15.4) | 2 (20.0) | 2 (33.3) | 5 (25.0) | 5 (9.1) |
Progressive disease | 19 (20.9) | 1 (10.0) | 0 | 5 (25.0) | 13 (23.6) |
Missing | 5 (5.5) | 2 (20.0) | 0 | 1 (5.0) | 2 (3.6) |
CI, confidence interval.
Overall response rate = complete response + partial response + nodular partial response.