Table 1.

Traumatic and non traumatic causes able to induce muscle tissue damage.

Traumatic causes	Non traumatic causes
Strenuous exercise	Infectious diseases (i.e. infectious sustained from influenza-A, coxsackie virus, CMV, EBV, rotavirus, enterovirus, HIV, Streptococcus beta haemoliticus, staphilococcus, Salmonella, Shigella, Legionella, Clostridium)
Direct muscle damage (i.e. injuries, delirium tremens, psycosis, seizures)	Metabolic diseases (ipokaliemia, ipophosphatemia, ipocalcemia)
Ischemic muscle damage (i.e. compartment syndrome, thrombosys, embolism)	Reumathic disorders (i.e polymyositis and dermatomyositis)
Myositis ossificans	Autoimmune diseases (myositis ossificans, rhabdomyolysis)
Neoplasms	Drug treatment (e.g. statins, theophilline, antiH1, benzodiazepines, amphotericine B, antidepressants)
Intramuscular abscess	Toxics (alcohol, cocaine, amphetamine, ecstasy) Radiation therapy Chronic denervation or disuse Sickle cell anemia