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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Crit Care Med. 2013 Apr;41(4):1075–1085. doi: 10.1097/CCM.0b013e318275d1f9

Table 2.

Top Canonical Pathways Induced by PT and TH.

2 Hours
IL-10 Signaling
Production of NO and ROS in Macrophages
IL-6 Signaling
NF-κB Signaling
iNOS Signaling
1Day
DNA Methylation & Transcriptional Repression Signaling
RhoGDI Signaling
Actin Nucleation by ARP-WASP Complex
Signaling by Rho Family GTPases
Cdc42 Signaling
3 Days
B Cell Receptor Signaling
PI3K Signaling in B Lymphocytes
Molecular Mechanisms of Cancer
T Cell Receptor Signaling
RANK Signaling in Osteoclasts