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. Author manuscript; available in PMC: 2013 Dec 1.
Published in final edited form as: J Thromb Haemost. 2012 Dec;10(12):2563–2572. doi: 10.1111/jth.12017

Fig. 6.

Fig. 6

Modified microparticles can deliver functional peroxisome proliferator-activated receptor-γ (PPARγ) to target cells. THP-1 cells were cultured for 24 h with no microparticles (No MP) or Meg-01 culture-derived green fluorescent protein (GFP)-positive microparticles (GFP MP) or PPARγ-overexpressing microparticles (PPARγ MP), in the presence of 0, 10, 100 or 1000 nM rosiglitazone alone (A), or with 10 μM GW9662 (B). Quantitative real-time PCR of mRNA was performed, and starting quantities of fatty acid-binding protein 4 (FABP4) were normalized to glyceraldehyde-3-phosphate dehydrogenase (GAPDH), and then subtracted from the value for the 0 nM concentration of each microparticle treatment group. Values were compared by use of two-way ANOVA and the Bonferroni post test. *P < 0.05, ***P < 0.001, ****P < 0.0001. NS, not significant.