Figure 8.

Benefit of cell therapy on contractile function. Cardiac function was evaluated by echocardiography and plotted individually (a) per animal (the red bars illustrate the means in each group), or globally (b) per group. Fractional shortenings were measured immediately before transplantation (baseline) and 30 and 60 days after injection with either culture medium (Sham, n = 8), ESC (ESC, n = 11), or D7 Mb (D7, n = 7). The animal labeled by the dash (#) was the only one found negative for X-Gal staining and was not included in calculations of means. In b, fractional shortening change was normalized by fractional shortening baseline in the respective group. ESC, embryonic stem cells; Mb, myoblasts.