Table I.

Trypanocidal activity, cytotoxicity, and selectivity indices of the chemical compounds

	Antitrypanocidal activity IC50 (µM)	Cytotoxicity IC50 (µM)	Selectivity index (Cytotoxicity/ Activity)
Nifurtimox	10.67 ± 1.01	114.0 ± 1.03	10.86 ± 0.93
IMDNQ1	2.77 ± 0.15	165.9 ± 1.24	60.25 ± 2.79
IMDNQ2	4.83 ± 0.60	253.7 ± 1.87	53.97 ± 5.95
IMDNQ3	0.70 ± 0.10	21.67 ± 1.45	31.83 ± 3.17
IMDNQ4	4.93 ± 0.64	35.50 ± 1.76	7.43 ± 0.97
IMDNQ5	2.27 ± 0.15	12.83 ± 0.73	5.70 ± 0.06
IMDNQ6	1.51 ± 0.01	14.17 ± 1.42	9.43 ± 0.94
IMDNQ7	1.27 ± 0.15	17.83 ± 2.21	14.23 ± 1.62
IMDNQ8	2.67 ± 0.33	26.50 ± 1.61	10.17 ± 0.97
IMDNQ9	4.07 ± 0.23	21.83 ± 1.88	5.43 ± 0.69
IMDNQ10	2.23 ± 0.15	610.9 ± 10.27	275.3 ± 13.73
IMDNQ11	6.10 ± 0.38	19.67 ± 3.71	3.20 ± 0.44

Each value represents the mean ± S.E. of three experiments.