Figure 1.

Serum concentration-time profiles of ciclesonide and des-CIC of ciclesonide measured on Day 7 at steady-state (per-protocol population). Serum concentration-time profiles of ciclesonide (broken line) and des-CIC of ciclesonide (solid line) measured on Day 7 at steady-state of each treatment period in 6 to 11-year-old pediatric patients with stable asthma (per-protocol population). Patients were allocated to a randomized treatment sequence. After using the treatment at home for 6 days, the patients returned to the study centre, before the next drug inhalation and pharmacokinetic evaluation on Day 7. The lower limit of quantification (LLOQ) for both compounds was 0.01 μg/L. Shown are Mean and Standard Error of the Mean.