Illustration of acyclovir determination in a synthetic sample contain several antiretroviral drugs (efavirenz, nevirapine, didanosine, lamivudine, zidovudine. and acyclovir, all with 2 ppm of concentration) by linear cyclic adsorptive stripping voltammetry. Supporting electrolyte, 10 mL of 2.0 × 10−3 mol L−1 NaOH. (A) addition of 200 μL of synthetic sample; (B–D) at each was an addition of 0.1 ppm of standard acyclovir.
Note: Condition time, 60 seconds at −0.9 V. Accumulation time, 60 seconds at −0.50 V. Potential final, −1.0 V. Scan rate, 100 mV s−1. Equilibrium time, 30 seconds. Thin-film mercury electrode (5 minutes at −0.9 V).