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. 2013 May 29;8(5):e65259. doi: 10.1371/journal.pone.0065259

Table 1. Correlation of spacer lengths and somatic activities of 15-RVD GoldyTALENs.

TALEN Pair* Spacer Length (bp) Somatic Activities (% chromosomal conversion)
IDH1 P1 16 86±3%*
FLT3 P1 16 84±5%*
FLT3 P2 15 83±4%*
NPM1B P1 LN 15 83±7%*
JAK2A P1 19 78±9%
NPM1B P1 RN 15 71±8%
FLT3 P3 14 67±6%
GFP(GM2) P1 19 52±4%
JAK2A P3 18 45±3%
NPM1A P1 13 38±4%
JAK2A P4 15 36±3%
NPM1A P2 18 35±6%
JAK2A P5 19 28±3%
JAK2A P2 16 24±3%
IDH1 P1 RM 17 15±4%
JAK2A P1 LM 18 9±3%
NPM1B P2 11 3±1%
NPM1B P1 12 4±1%
*

shown in decreasing order of activity.

modified without the 5′ T nucleotide at one of the TALEN arms.