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Changes in adhesion molecules. Mechanical ventilation using high pressures increased the levels of E-selectin (A) and ICAM-1 (B) in lung tissue homogenates. Clarithromycin dampened the increase in E-selectin after VILI. Representative western blots are shown in panel C. *p < 0.05 in post-hoc tests compared to low-pressure ventilated counterparts.
