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. 2013 May 29;8(5):e58867. doi: 10.1371/journal.pone.0058867

Table 2. Odds ratios (ORs) for TNM classes in postmenopausal breast cancer by age at first and last childbirth, stratified by time interval between first and last childbirth.

Age at breast cancer diagnosis T1 Tis* vr. T1 T2–T4** vr. T1 N0 N1–N3 vr. N0 M0 M1 vr. M0
N N OR (95%CI) P N OR (95%CI) P N N OR (95%CI) P N N OR (95%CI) P
Time interval between first and last childbirth 1-4 yearsAge at first childbirth (year)
20-29 (Ref.) 2,574 55 1.00 1,503 1.00 2,607 1,145 1.00 2,863 75 1.00
≤19 277 5 0.84 (0.33–2.13) 0.71 138 0.08 (0.71–1.10) 0.25 20 132 1.14 (0.92–1.42) 0.24 23 5 0.63 (0.25–1.58) 0.33
30–39 569 13 1.00 (0.54–1.87) 1.00 415 1.14 (0.99-1.32) 0.09 1,574 252 0.90 (0.77–1.06) 0.21 1,679 31 1.61 (1.04–2.50) 0.03
≥40 9 0 12 2.22 (0.91–5.40) 0.08 58 7 1.79 (0.70–4.58) 0.23 75 1 2.96 (0.37–23.62) 0.31
Total 3,429 73 2,068 1,574 1,536 4,640 112

Bold type: 95% CI does not include 1.00.

Women with two or more children were included. ORs were adjusted for parity, region and occupation.

*

Carcinoma in situ.