Table 2. Odds ratios (ORs) for TNM classes in postmenopausal breast cancer by age at first and last childbirth, stratified by time interval between first and last childbirth.
Age at breast cancer diagnosis | T1 | Tis* vr. T1 | T2–T4** vr. T1 | N0 | N1–N3 vr. N0 | M0 | M1 vr. M0 | ||||||||
N | N | OR (95%CI) | P | N | OR (95%CI) | P | N | N | OR (95%CI) | P | N | N | OR (95%CI) | P | |
Time interval between first and last childbirth 1-4 yearsAge at first childbirth (year) | |||||||||||||||
20-29 (Ref.) | 2,574 | 55 | 1.00 | 1,503 | 1.00 | 2,607 | 1,145 | 1.00 | 2,863 | 75 | 1.00 | ||||
≤19 | 277 | 5 | 0.84 (0.33–2.13) | 0.71 | 138 | 0.08 (0.71–1.10) | 0.25 | 20 | 132 | 1.14 (0.92–1.42) | 0.24 | 23 | 5 | 0.63 (0.25–1.58) | 0.33 |
30–39 | 569 | 13 | 1.00 (0.54–1.87) | 1.00 | 415 | 1.14 (0.99-1.32) | 0.09 | 1,574 | 252 | 0.90 (0.77–1.06) | 0.21 | 1,679 | 31 | 1.61 (1.04–2.50) | 0.03 |
≥40 | 9 | 0 | 12 | 2.22 (0.91–5.40) | 0.08 | 58 | 7 | 1.79 (0.70–4.58) | 0.23 | 75 | 1 | 2.96 (0.37–23.62) | 0.31 | ||
Total | 3,429 | 73 | 2,068 | 1,574 | 1,536 | 4,640 | 112 |
Bold type: 95% CI does not include 1.00.
Women with two or more children were included. ORs were adjusted for parity, region and occupation.
Carcinoma in situ.