. 2013 Apr 17;19(1):99–108. doi: 10.2119/molmed.2013.00009

Table 1.

Phenotype of human myeloma cell lines.

Cell line	CD38^a	CD56^a	CD138^a	PC-1/CD203a^a	OTR^b
DL06^c	+	−	+/−	−	+
LP-1^d	⁺⁺	−	+	−	+
JJN3^e	+	−	+	−	⁺⁺
U266^e	−	−	+	−	+/−
OPM-2^e	+	+	+	+/−	+
IM9^e	+/−	−	±	−	+
NCI-H929^e	⁺⁺	+/−	+/−	−	+

++, High intensity; +, medium intensity; −, no staining; +/−, low to nil staining.

CD38, CD56 and CD138 were selected as accepted markers of myeloma transformation.

PC-1/CD203a and OTR (oxytocin receptor) were included as original observations of the lab (A Chillemi, G Zaccarello, V Quarona, Mirca Lazzaretti, Eugenia Martella, Nicola Giuliani, Riccardo Ferracini, Vito Pistoia, AL Horenstein and F Malavasi, unpublished data) (67).

DL06 was stabilized from cells obtained from a pleural effusion of an aggressive, therapy-refractory plasma cell leukemia patient. These cells maintain a high secretion in vitro of the monoclonal protein seen in patient blood (namely, IgAλ).

LP-1 cell line was produced in collaboration with the lab of L Pegoraro (University of Torino) (66).

JJN3, U266, OPM-2, IM9 and NCI-H929 cell lines were obtained from ATCC (Manassas, VA, USA).