Table 1.
Non-DM | Prevalent DM | p-Value | |
---|---|---|---|
(N = 6458) | (N = 409) | ||
Age (years) | 70.7 ± 4.7 | 71.0 ± 4.6 | 0.35 |
Weight (kg) | 67.1 ± 12.0 | 72.6 ± 14.8 | <0.001 |
Change in weight (V6-BL) (%/year) | −0.25 ± 0.96 | −0.41 ± 0.99 | 0.012 |
Height (cm) | 159.6 ± 5.9 | 158.9 ± 6.1 | 0.017 |
Height loss since age 25 (cm) | 3.1 ± 2.8 | 2.9 ± 2.6 | 0.095 |
Years since menopause (years) | 23.6 ± 7.8 | 24.7 ± 8.1 | 0.006 |
Current smoker | 573 (8.9) | 34 (8.3) | 0.69 |
Current vitamin D use | 2958 (46.6) | 149 (36.9) | <0.001 |
Current calcium use | 2871 (44.6) | 134 (32.8) | <0.001 |
Current estrogen use | 1226 (19.5) | 42 (10.4) | <0.001 |
Alendronate taken in last 2 years (V6) | 479 (8.9) | 18 (6.6) | 0.18 |
Current raloxifene use (V6) | 8 (0.2) | 1 (0.4) | 0.36 |
Current thiazide use | 1513 (23.7) | 153 (37.8) | <0.001 |
Current statin use (V4) | 248 (3.9) | 22 (5.5) | 0.12 |
Current oral steroid use | 110 (1.7) | 4 (1.0) | 0.27 |
Grip strength (kg) | 21.3 ± 4.1 | 20.8 ± 4.4 | 0.020 |
Walking speed (m/s) | 1.05 ± 0.20 | 0.96 ± 0.21 | <0.001 |
Inability to rise from chair | 142 (2.2) | 14 (3.4) | 0.10 |
Walk for exercise | 3478 (53.9) | 189 (46.2) | 0.003 |
Poor light touch discrimination (V2) | 240 (4.3) | 35 (9.9) | <0.001 |
Baseline BMD | |||
Calcaneus BMD (g/cm2) | 0.41 ± 0.09 | 0.44 ± 0.10 | <0.001 |
Distal radius BMD (g/cm2) | 0.36 ± 0.08 | 0.39 ± 0.08 | <0.001 |
Proximal radius BMD (g/cm2) | 0.64 ± 0.1 | 0.67 ± 0.1 | <0.001 |
Femoral neck BMD (V2) (g/cm2) | 0.65 ± 0.11 | 0.69 ± 0.12 | <0.001 |
Total hip BMD (V2) (g/cm2) | 0.76 ± 0.13 | 0.81 ± 0.14 | <0.001 |
Total lumbar spine BMD (V2) (g/cm2) | 0.86 ± 0.17 | 0.9 ± 0.17 | <0.001 |
Mean (SD), or N (%). BMD, bone mineral density; DM, diabetes mellitus.
aMeasurement at baseline visit unless otherwise indicated.