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Plasma total ghrelin levels during continuous iv infusions (−15 to 225 minutes) of saline and 0.2 or 0.6 nmol kg−1 h−1 acyl ghrelin in healthy men and women. A bolus iv dose of glucose (11.4 g/m2 body surface area) was infused over 1 minute after plasma ghrelin had reached a steady state (at 45 minutes). The acyl ghrelin infusions resulted in a dose-dependent increase in plasma total ghrelin concentrations. ***, P < .001, ghrelin vs saline.
