Skip to main content
. 2013 Apr 19;2(1):172. doi: 10.1186/2193-1801-2-172

Table 2.

Type of interactions and interacting amino acid residues of COX-2 protein with selected ligands

COX-2 Protein H-Bonding V-waal Pi-pi Pi-sigma Pi-cation
Cycloprodigiosin Tyr324 ----- Phe487 ----- Arg89
Prodigiosin Leu321, Tyr324 ----- ----- ----- -----
Rofecoxib ----- ----- ----- ----- Arg89
Celecoxib His58, tyr324, gln161, leu321 ----- ----- ----- Arg89