Table 2.

HLA class II frequencies and number of CEA peptides that bind to each allele’s gene product

Allele	HLA-DRB1										HLA-DRB3–5
	DRB1*0101–06	DRB1*0301–13	DRB1*0401–32	DRB1*0701–04	DRB1*0802–21	DRB1*0901	DRB1*1101–35	DRB1*1301–34	DRB1*1501–08	Total coverage DRB1	DRB3*0101	DRB4*0101	DRB5*0101	Total coverage DRB3–5	Predicted response rate (%)a
Caucasoids	9.4b	11.1	12.8	13.2	3.7	2.0	13.4	10.2	10.8	69.2	53.2	50.9	23.9	93.4	97
Blacks	5.5	14	10.5	9.23	4.8	2.0	15.7	14.3	9.9	69.0	55.2	21.1	16.5	77.8	84
Asian	3.0	5	13	5.8	6.5	9.4	7.8	4.9	14.4	58.7	54.2	48.9	22.0	92.4	98
Estimated average	6	10	12	9	5	5	12	10	12	65.8	54.2	40.3	20.8	88.5	94
# of epitopes	4c	2	4	4	2	1	3	4	3	3	1	1	2	1

^aPredicted percentage of population that could respond to at least one epitope

^bFrequency of allele the population

^cNumber of epitopes in the CEA pool that bind to this HLA-DR variant