Table 1.
Demographic and clinical characteristics by gender.
| Men N=385,103 |
Women N=185,674 |
P-value | |
|---|---|---|---|
|
| |||
| Demographics | |||
| Age, years, mean (SD) | 63.3 (11.8) | 67.1 (12.3) | <0.01 |
| White | 89.5 | 86.0 | <0.01 |
|
| |||
| Clinical Characteristics | |||
| Body mass index, mean (SD) | 29.8 (5.9) | 30.4 (7.4) | <0.01 |
| Body surface area, mean (SD) | 2.1 (0.2) | 1.8 (0.2) | <0.01 |
|
| |||
| New York Heart Association class | <0.01 | ||
| I | 13.5 | 10.6 | |
| II | 31.6 | 29.3 | |
| III | 34.9 | 36.5 | |
| IV | 19.4 | 23.1 | |
|
| |||
| Coronary artery disease risk factors | |||
| Diabetes | 32.4 | 39.8 | <0.01 |
| Hypertension | 78.9 | 85.0 | <0.01 |
| Dyslipidemia | 79.2 | 78.9 | 0.04 |
| Current/Recent Smoker | 28.5 | 25.9 | <0.01 |
| Family history of coronary disease | 24.3 | 25.5 | <0.01 |
|
| |||
| Coronary artery disease history | |||
| Previous PCI | 34.9 | 31.1 | <0.01 |
| Previous CABG | 19.1 | 13.6 | <0.01 |
| Myocardial infarction | 27.8 | 23.6 | <0.01 |
|
| |||
| Other cardiovascular disease history | |||
| Congestive heart failure | 9.5 | 12.7 | <0.01 |
| Cerebrovascular disease | 10.2 | 16.1 | <0.01 |
| Peripheral vascular disease | 11.1 | 13.0 | <0.01 |
| Previous valve surgery | 1.4 | 1.4 | 0.80 |
|
| |||
| Other disease history | |||
| Chronic lung disease | 12.9 | 17.6 | <0.01 |
| Previous renal failure | 1.9 | 2.6 | <0.01 |
|
| |||
| Test information, mean (SD) | |||
| Estimated glomerular filtration rate | 78.7 (30.2) | 70.8 (30.1) | <0.01 |
| Left ventricular ejection fraction | 51.2 (12.1) | 54.8 (12.1) | <0.01 |
| Pre-procedural hemoglobin (g/dL) | 14.1 (1.8) | 12.7 (1.7) | <0.01 |
|
| |||
| Estimated pre-procedural bleeding risk* | |||
| Mean bleeding risk %, (SD) | 4.0 (3.9) | 8.0 (7.l) | <0.01 |
| Categories of risk | <0.01 | ||
| High (>5%) | 23.3 | 54.1 | |
| Intermediate (2.3–5.0%) | 30.7 | 38.9 | |
| Low (<2.3%) | 46.0 | 7.0 | |
Based on NCDR Bleeding risk model v4 which accounts for age, gender, body mass index, previous cerebrovascular disease, chronic lung disease, previous PCI, peripheral vascular disease, diabetes mellitus, left ventricular ejection fraction, chronic kidney disease, cardiogenic shock, PCI status, ST-elevation myocardial infarction, non-ST-elevation myocardial infarction, cardiac arrest within 24 hours, pre-procedure New York Heart Association Class IV, estimated glomerular filtration rate, pre-procedure hemoglobin, pre-procedure TIMI flow, number of diseased vessels, use of lytics prior to PCI, subacute stent thrombosis, Society for Cardiovascular Angiography and Intervention lesion class, and lesion location.
SD = standard deviation; PCI = percutaneous coronary intervention; CABG = coronary artery bypass grafting; TIMI = Thrombolysis in Myocardial Infarction