(a) The Ag+ ion concentration of suspensions containing the dispersed uncoated (red triangles) and SiO2-coated (blue circles) Ag/Fe2O3 particles as determined from ISE (open symbols) and DGT (filled symbols). The ISE values of the de-ionized water are also shown (gray broken line). There is significant release of toxic Ag+ ions for the uncoated samples, while for the coated ones it is minimized. The error bars correspond to the standard deviation of at least three measurements. (b) The cytotoxicity evaluation of the uncoated and SiO2-coated 35Ag/Fe2O3 biomarker incubated at 37 °C for 24 hours at concentrations 5, 2.5, 1.25, 0.625 mg/L of Ag. The positive (toxic drug inducing apoptosis, Staurosporin) and negative controls are also shown. The error bars correspond to the standard deviation of triplicates.