Fig. 2.

Expression of NRs early in osteoblastic differentiation. QPCR analysis of NRs regulated at a ≥ 1.5-fold threshold (upregulated or downregulated) and containing at least one statistically significant timepoint (p ≤ 0.05) was conducted in primary mouse calvarial osteoblasts collected at 0, 2, 6, 12, and 24 hours following induction of osteoblastic differentiation (n=4). The genes were grouped by their expression characteristics; (A) upregulated at 2 hours, (B) NRs displaying a biphasic response, (C) upregulated from 6 to 24 hours, and (D) downregulated from 2 to 24 hours. Figure legends within each graph describe the graph labels. Strictly for figure clarity, SEs and p-values have been omitted but the data conform to the above statistical standards (≥ 1.5-fold threshold and p ≤ 0.05, at least at one timepoint).