Fig. 4. Opposite effects of an L-type Ca2+ inhibitor and activator on calcium transients in hiPSC-CMs.
(a,b) Average calcium transient curves (left) and dose-response plot (right) for the FWHM in hiPSC-CMs treated with the L-type Ca2+ channel blocker verapamil (a) or channel activator Bay K 8644 (b). Calcium transients were averaged between well replicates and aligned at the beginning of the upstroke.