Table 1.
Cell numbers in the peritoneal cavity of normal and mutant mice (ΔD-DFL)
| N | Total Cells × 106 | CD19+ × 106 | Fraction
|
|||
|---|---|---|---|---|---|---|
| B1a × 105 | B1b × 105 | B2 × 105 | ||||
| wt/wt | 9 | 3.9 (0.1) | 1.3 (0.1) | 3.9 (0.3) | 1.1 (0.1) | 3.9 (0.3) |
| ΔD-DFL/ΔD-DFL | 9 | 4.1 (0.2) | 1.2 (0.1) | 3.5 (0.3) | 1.0 (0.1) | 3.3 (0.2) |
| Cell numbers in the peritoneal cavity of normal and mutant mice (ΔD-iD)
| ||||||
|---|---|---|---|---|---|---|
| N | Total Cells × 106 | CD19+ × 106 | Fraction
|
|||
| B1a × 105 | B1b × 105 | B2 × 105 | ||||
| wt/wt | ||||||
| ΔD-iD/ΔD-iD | ||||||
| Cell numbers in the peritoneal cavity of normal and mutant mice (ΔD-rf2)
| ||||||
|---|---|---|---|---|---|---|
| N | Total Cells × 106 | CD19+ × 106 | Fraction
|
|||
| B1a × 105 | B1b × 105 | B2 × 105 | ||||
| wt/wt | 10 | 3.8 (0.2) | 1.4 (0.1) | 2.3 (0.3) | 1.9 (0.2) | 4.2 (0.4) |
| ΔD-rf2/ΔD-rf2 | 10 | 4.0 (0.2) | 1.4 (0.1) | 2.2 (0.2) | 2.0 (0.1) | 4.5 (0.2) |
| Cell numbers in the peritoneal cavity of normal and mutant mice (C56/BL/6, sle2, ΔD-iD)
| ||||||
|---|---|---|---|---|---|---|
| N | Total Cells × 106 | CD19+ × 106 | Fraction
|
|||
| B1a × 105 | B1b × 105 | B2 × 105 | ||||
| wt/wt | 10 | 5.0 (0.2) | 1.3 (0.1) | 5.4 (0.5) | 2.7 (0.3) | 1.8 (0.2) |
| ΔD-iD/ΔD-iD | 10 | 4.9 (0.2) | 1.1 (0.1) | 4.6 (0.6) | 2.1(0.3) | 1.5 (0.1) |
Total nucleated cells that excluded trypan blue. Values shown are cell counts per first peritoneal cavity lavage (average cellularity of per peritoneal cavity collected from each experimental animal) of paired 8 week old homozygous ΔD-rf2 (ΔD-rf2) or homzogyous wild-type (WT) littermate progeny of heterozygous ΔD-rf2/WT BALB/c mice. The standard error of the mean is presented in parentheses. The number of cells in fractions B1a (CD19+ CD5+ Mac 1+), B1b (CD19+ CD5− Mac-1+), and B2 (CD19+ CD5− Mac-1−) was determined from the relative proportion of total cells.
*
p ≤ 0.05.
**
p ≤ 0.01,
***
p ≤ 0.005,
****
p ≤ 0.0001 versus BALB/c WT littermate.