Fig. 7.

Estimated longitudinal atrophy rate from patients (red), controls (blue) and between repeat scans (green) from HF-MRI in hippocampal subfields. Atrophy rates are averaged over left and right sides. A value of 0.01 indicates 1% annualized loss in subfield volume. Error bars represent standard deviation. In the bar graphs on the left,“*”s on top of an error bar indicate significant non-zero atrophy rate measurement for the corresponding subject group, and those over the line connecting the bar graphs for two groups indicate significant cross-sectional difference in atrophy rates between the groups (patients > controls). In each case, effect size Δ and sample size estimate N (Eqs. (5) and (6)) are also shown.