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. Author manuscript; available in PMC: 2013 May 30.
Published in final edited form as: Am J Transplant. 2011 Nov 9;12(2):313–321. doi: 10.1111/j.1600-6143.2011.03836.x

Figure 1. NK depletion inhibits DSA induced CAV in B6.RAG1−/−C3−/−recipients.

Figure 1

The severity of coronary lesions in B10.BR heart allografts in B6.RAG1−/− C3−/− recipients given DSA (anti-H-2Kk; clone 36–7–5) is compared with and without anti-NK1.1 mAb treatment. The neointimal index was significantly less in the anti-H-2KkIgG2a mAb treatment group given anti-NK1.1. The severity of coronary lesions in anti-H-2Kk IgG2a plus anti-NK1.1 mAb is similar to that of the no treatment group, 8.3% versus 7.2%. The p values were calculated with the Mann–Whitney U test. The numbers in the parenthesis indicate the numbers of the hearts examined. The number adjacent to the block column indicates the median value of the neointimal index in each group.