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Effects of F(ab’)2 and intact DSA on CAV
| Group | Donor | Recipient | Treatment | Frequency of CAV | p-Value |
|---|---|---|---|---|---|
| 1 | B10.BR | B6.RAG1−/− | αH-2Kk(IgG2a) | 5/5 | |
| 2 | αH-2Kk(IgG2a) + αNK1.1 | 2/5 | versus group 1 NS | ||
| 3 | F(ab’)2 fragment of αH-2Kk(IgG2a) ab + αNK1.1 | 0/5 | versus group 1 p < 0.01 | ||
| 4 | F(ab’)2 fragment of αH-2Kk(IgG2a) ab + αH-2Kk(IgG2a; 1 dose) | 0/3 | |||
| 5 | B6.RAG1−/− | B6.RAG1−/− | αH-2Kk(IgG2a) | 0/6 | versus group 1 p < 0.01 |
