Table 3.
Effects of intact and F(ab’)2 DSA and NK depletion on pERK expression
| pERK Expression (% of cells) Endothelium |
||||||||
|---|---|---|---|---|---|---|---|---|
| Group | Donor | Recipient | Treatment | N | Arterial | Capillary | Myocyte | p-Value |
| 1 | B10.BR | B6.RAG1−/− | αH-2Kk(IgG2a) | 5 | 63 ±34 | 44±15 | 44 ±27 | versus group 3 p < 0.01 (all categories) |
| 2 | B10.BR | B6.RAG1−/− | αH-2Kk(IgG2a) + αNK1.1 | 5 | 34±18 | 25±29 | 17 ± 20 | versus group 1 p > 0.05 (all categories) |
| 3 | B10.BR | B6.RAG1−/− | αH-2Kk(IgG2a) F(ab’)2 | 5 | 7±8 | 2±4 | 2 ± 2 | versus group 4 p > 0.05 (all categories) |
| 4 | B6.RAG1−/− | B6.RAG1−/− | αH-2Kk(IgG2a) | 2 | 5±2 | 3±3 | 21 ±9 | |