Figure 1.
Linkage Disequilibrium Pattern of Single-Nucleotide Polymorphisms in ABCA7 Based on the HapMap Reference Sample (African Americans in the Southwest USA) and NCBI36/hg18 Genome Build
Black arrows indicate single-nucleotide polymorphisms (SNPs) previously reported to be associated with Alzheimer disease in whites3,5 (the top hit reported by Hollingworth et al [rs3752228] may have changed if the entire cohort had been genotyped in stages 2 and 3). Pink arrow indicates the location of rs115550680 associated with Alzheimer disease in the present study.The SNPs shown in blue are not represented in HapMap. Kb indicates kilobase.