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. 2013 May 30;9(5):e1003520. doi: 10.1371/journal.pgen.1003520

Table 3. Narrow-sense heritability explained by genotyped SNPs (Inline graphic) for dichotomous phenotypes on the liability scale.

Phenotype Inline graphic s.e. Prevalence Inline graphic
Alcohol Dependence 0.235 0.030 0.07
Asthma 0.264 0.067 0.13
Autoimmune Systemic RA SLE SSc AS 0.200 0.048 0.02
Autoimmune Tcell mediated 0.192 0.033 0.05
Breast Cancer 0.117 0.051 0.12
Coronary Artery Disease 0.146 0.017 0.06 0.39(0.06)
Hypertension in Pregnancy 0.083 0.043 0.03
Osteoarthritis 0.126 0.026 0.1
Prostate Cancer 0.204 0.056 0.09
Rheumatoid Arthritis** 0.261 0.061 0.01 0.63(0.06)0.32(0.07)*
Type 2 Diabetes 0.254 0.041 0.08 0.44(0.06)

Inline graphic are previously reported estimates of Inline graphic with standard errors given in ()'s.

*

RA estimate without the MHC region.

**

RA in our study contained a mixture CCP positive and negative cases, while the previously published worked is based on CCP positive cases only [34].