Table 3. Narrow-sense heritability explained by genotyped SNPs () for dichotomous phenotypes on the liability scale.
Phenotype | s.e. | Prevalence | ||
Alcohol Dependence | 0.235 | 0.030 | 0.07 | |
Asthma | 0.264 | 0.067 | 0.13 | |
Autoimmune Systemic RA SLE SSc AS | 0.200 | 0.048 | 0.02 | |
Autoimmune Tcell mediated | 0.192 | 0.033 | 0.05 | |
Breast Cancer | 0.117 | 0.051 | 0.12 | |
Coronary Artery Disease | 0.146 | 0.017 | 0.06 | 0.39(0.06) |
Hypertension in Pregnancy | 0.083 | 0.043 | 0.03 | |
Osteoarthritis | 0.126 | 0.026 | 0.1 | |
Prostate Cancer | 0.204 | 0.056 | 0.09 | |
Rheumatoid Arthritis** | 0.261 | 0.061 | 0.01 | 0.63(0.06)0.32(0.07)* |
Type 2 Diabetes | 0.254 | 0.041 | 0.08 | 0.44(0.06) |
are previously reported estimates of with standard errors given in ()'s.
RA estimate without the MHC region.
RA in our study contained a mixture CCP positive and negative cases, while the previously published worked is based on CCP positive cases only [34].