Figure 2. The majority of chlamydial antigens recognized during primary infection and re-challenge are shared between trachoma serovars.

RIP was performed using lysates made from C. trachomatis serovars A2497 and Ba. Serum from monkey RML134 was used in the experiment and four representative time points throughout the course of infection and re-challenge were analyzed. Antibody to MOMP was serovar-specific, reacting most intensely with the infecting A2497strain. Conversely, antibody reactivity against the other immunogenic proteins was cross-reactive between trachoma serovars demonstrating that these antigens are conserved.