Table 1. Effect of acute saline or CNF1 icv with regards to Elevated Plus Maze (EPM) behavior.

Treatment and Strain	Total Entries (TE)	% Open Time (%OT)	% Open Entries (%OT)
Saline-apoE3	28.35±9.83	34.73±15.67	48.19±11.49
CNF1-apoE3	22.92±7.29	30.25±17.78	47.72±10.64
Saline-apoE4	28.28±7.01	32.14±14.52	44.78±9.49
CNF1-apoE4	28.38±9.93	29.55±13.42	47.84±9.52

Data (mean±SEM) are shown for apoE3 or apoE4 acutely treated with CNF1 (0.1 nM icv) or saline (icv). CNF1 or saline treatment did not induce any changes in anxiety like-behavior. For detailed statistical analysis, see Results.